Potassium Hydroxide → HCID 14388650, 화합물

HRID 648877

반응식

HRID 648877 반응식
[F:1][C:2]1[CH:3]=[C:4]([C:9]2[CH:14]=[CH:13][C:12]([C:15](=[O:17])[CH3:16])=[CH:11][CH:10]=2)[CH:5]=[CH:6][C:7]=1[OH:8].[OH-].[K+].C1(C)C=CC(S(O[CH:30]([CH3:37])[CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH3:36])(=O)=O)=CC=1>C(O)C>[F:1][C:2]1[CH:3]=[C:4]([C:9]2[CH:14]=[CH:13][C:12]([C:15](=[O:17])[CH3:16])=[CH:11][CH:10]=2)[CH:5]=[CH:6][C:7]=1[O:8][CH:30]([CH3:37])[CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH3:36]

참가 물질

5

반응물 3

HCID 14797Potassium HydroxideHCID 3912199p-Toluenesulfonic acid 1-methylheptyl esterHCID 143886491-(3'-Fluoro-4'-hydroxy[1,1'-biphenyl]-4-yl)ethan-1-one

생성물 1

HCID 14388650HCID 14388650, 화합물수율 28.6%

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

3'-Fluoro-4'-hydroxy-4-acetylbiphenyl (15 g), potassium hydroxide (4.0 g), ethanol (370 ml), optically active 1-methylheptyl p-toluenesulfonate (20.5 g), were heated for 5 hrs. under reflux, to obtain by usual work-up, 6.37 g of 3'-fluoro-4'-(1-methylheptyloxy)-4-acetylbiphenyl, m.p. 67.6°~68.5° C.

후처리

  1. temperatureunder reflux

출처 및 근거

ORD 기록
ord-c3224b82c6964637ab80d88d817d7c0d
출처 데이터셋
uspto-grants-1988_04
특허 번호
US04737313

연결된 노트

불러오는 중…