p-Toluenesulfonic acid → Isobutyl-4-(Propylthio)Butyrate

HRID 649351

반응식

HRID 649351 반응식
[CH3:1][O:2][C:3](=[O:11])[CH2:4][CH2:5][CH2:6][S:7][CH2:8][CH2:9][CH3:10].[CH2:12](O)[CH:13](C)[CH3:14].C1(C)C=CC(S(O)(=O)=O)=CC=1>>[CH2:1]([O:2][C:3](=[O:11])[CH2:4][CH2:5][CH2:6][S:7][CH2:8][CH2:9][CH3:10])[CH:13]([CH3:14])[CH3:12]

참가 물질

4

반응물 3

HCID 6101p-Toluenesulfonic acidHCID 6560IsobutanolHCID 20143889Methyl-4-(Propylthio)Butyrate

생성물 1

HCID 20143891Isobutyl-4-(Propylthio)Butyrate

실험 절차

Into a 25 mm micro flask equipped with spin bar, hot plate (having built in magnetic stirrer), reflux condenser and thermometer are placed 5 grams (0.0284 moles) of methyl-4-(propylthio)butyrate; 8.4 grams (0.1136 moles) of isobutanol and 0.05 grams of para-toluene sulfonic acid. The reaction mass is heated to reflux and maintained at reflux with stirring for a period of 14.5 hours. At the end of the refluxing, the reaction mass is cooled and distilled on a micro Vigreux column yielding the following fractions:

후처리

  1. customInto a 25 mm micro flask equipped with spin bar
  2. temperaturehot plate (having built in magnetic stirrer), reflux condenser
  3. temperatureThe reaction mass is heated
  4. temperatureto reflux
  5. temperaturemaintained
  6. temperatureat reflux
  7. temperatureAt the end of the refluxing, the reaction mass is cooled
  8. distillationdistilled on a micro Vigreux column
  9. customyielding the following fractions

출처 및 근거

ORD 기록
ord-890cc47db4dc40c9b782c98ba057f760
출처 데이터셋
uspto-grants-1988_04
특허 번호
US04739105

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