Acetic Anhydride → 5-acetoxy-12H-benzo[a]phenothiazine
반응식
[C:1]([O:4][C:5](=[O:7])[CH3:6])(=O)[CH3:2].OC1[CH:22]=[C:21]2[C:12]([NH:13][C:14]3[C:19]([S:20]2)=[CH:18][CH:17]=[CH:16][CH:15]=3)=[C:11]2C=[CH:24][CH:25]=[CH:26][C:10]=12>N1C=CC=CC=1>[C:5]([O:4][C:1]1[CH:22]=[C:21]2[C:12]([NH:13][C:14]3[C:19]([S:20]2)=[CH:18][CH:17]=[CH:16][CH:15]=3)=[C:11]2[CH:10]=[CH:26][CH:25]=[CH:24][C:2]=12)(=[O:7])[CH3:6]참가 물질
4
실험 절차
Acetic anhydride (2 ml) was added to a solution of 5-hydroxy-12H-benzo[a]phenothiazine (1) (1.4 gm) in pyridine (10 ml) and stirred for 15 minutes. The reaction mixture was concentrated under vacuum and ice-water was added to the residue. The resulting precipitate was filtered, air-dried and washed with ethyl acetate to afford the title compound.
후처리
- concentrationThe reaction mixture was concentrated under vacuum and ice-water