Methyl iodide → 7-Amino-2-methyl-3,4-dihydroisoquinolinium iodide
반응식
[NH2:1][C:2]1[CH:11]=[C:10]2[C:5]([CH2:6][CH2:7][N:8]=[CH:9]2)=[CH:4][CH:3]=1.[I:12][CH3:13]>CC(C)=O>[I-:12].[NH2:1][C:2]1[CH:11]=[C:10]2[C:5]([CH2:6][CH2:7][N+:8]([CH3:13])=[CH:9]2)=[CH:4][CH:3]=1참가 물질
4
실험 절차
7-amino-3,4-dihydroisoquinoline (0.40 g, 2.74 mmol) in acetone (125 ml) was treated with iodomethane (0.50 ml, 8.03 mmol) and left stirring at room temperature for 18 h. The resultant yellow precipitate was collected by filtration and dried in vacuo at ambient temperature (0.73 g, 92%). m/z (API)=161 (M)+
후처리
- waitleft
- filtrationThe resultant yellow precipitate was collected by filtration
- customdried in vacuo at ambient temperature (0.73 g, 92%)
출처 및 근거
- ORD 기록
- ord-a31009c6874141d691607b362acda856
- 출처 데이터셋
- uspto-grants-2001_08
- 특허 번호
- US06277861B1
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