Sodium Hydroxide → 3-Chloro-4-(propan-2-yloxy)benzoic acid

HRID 650955

반응식

HRID 650955 반응식
[Cl:1][C:2]1[CH:3]=[C:4]([CH:9]=[CH:10][C:11]=1[O:12][CH:13]([CH3:15])[CH3:14])[C:5]([O:7]C)=[O:6].[OH-].[Na+]>CO>[Cl:1][C:2]1[CH:3]=[C:4]([CH:9]=[CH:10][C:11]=1[O:12][CH:13]([CH3:15])[CH3:14])[C:5]([OH:7])=[O:6]

참가 물질

4

반응물 2

HCID 14798Sodium HydroxideHCID 22597811Methyl 3-chloro-4-isopropoxybenzoate

생성물 1

HCID 225977283-Chloro-4-(propan-2-yloxy)benzoic acid수율 83.1%

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

Methyl 3-chloro-4-isopropoxybenzoate (5.5 g, 24.1 mmol) was hydrolysed using 1M NaOH (36 ml) in methanol (80 ml). Extraction and work-up with ethyl acetate gave the title compound (4.3 g).

후처리

  1. extractionExtraction

출처 및 근거

ORD 기록
ord-03d26cef444145b4b90392f768129125
출처 데이터셋
uspto-grants-2001_08
특허 번호
US06277861B1

연결된 노트

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