2,4-Dimethoxybenzoic acid → 5-Bromo-2,4-dimethoxybenzoic acid

HRID 650958

반응식

HRID 650958 반응식
[CH3:1][O:2][C:3]1[CH:11]=[C:10]([O:12][CH3:13])[CH:9]=[CH:8][C:4]=1[C:5]([OH:7])=[O:6].[Br:14]Br>C(Cl)(Cl)Cl>[Br:14][C:9]1[C:10]([O:12][CH3:13])=[CH:11][C:3]([O:2][CH3:1])=[C:4]([CH:8]=1)[C:5]([OH:7])=[O:6]

참가 물질

4

반응물 2

HCID 70522,4-Dimethoxybenzoic acidHCID 24408Bromine

생성물 1

HCID 135050975-Bromo-2,4-dimethoxybenzoic acid수율 50%

시약·촉매·용매 1

HCID 6212Chloroform용매2회

실험 절차

To a solution of 2,4-dimethoxybenzoic acid (4.0 g, 0.022 mol) in chloroform (60 ml) was added bromine (1.13 ml, 0.022 mol) in chloroform (20 ml) dropwise. After stiring overnight at room temperature the precipitate was filtered off and dried to afford the title compound as a white solid (2.87 g).

후처리

  1. filtrationthe precipitate was filtered off
  2. customdried

출처 및 근거

ORD 기록
ord-8aeaaf75fafb491db2f817b3286f1927
출처 데이터셋
uspto-grants-2001_08
특허 번호
US06277861B1

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