Itaconic acid → 3-(Benzothiazol-2-ylthio)-propane-1,2-dicarboxylic acid

HRID 65123

반응식

HRID 65123 반응식
[Al+3].[Cl-].[Cl-].[Cl-].[SH:5][C:6]1[S:7][C:8]2[CH:14]=[CH:13][CH:12]=[CH:11][C:9]=2[N:10]=1.[C:15]([OH:23])(=[O:22])[C:16]([CH2:18][C:19]([OH:21])=[O:20])=[CH2:17].O>C(OCC)C.C(OCC)(=O)C>[S:7]1[C:8]2[CH:14]=[CH:13][CH:12]=[CH:11][C:9]=2[N:10]=[C:6]1[S:5][CH2:17][CH:16]([C:15]([OH:23])=[O:22])[CH2:18][C:19]([OH:21])=[O:20]

참가 물질

7

반응물 4

HCID 811Itaconic acidHCID 962WaterHCID 6451240Aluminum(III) ChlorideHCID 178418395HCID 178418395, 화합물

생성물 1

HCID 194275373-(Benzothiazol-2-ylthio)-propane-1,2-dicarboxylic acid수율 50.5%

시약·촉매·용매 2

HCID 3283Diethyl Ether용매2회HCID 8857Ethyl Acetate용매

실험 절차

13.3 g of AlCl3 are dissolved in 100 ml of diethyl ether at 0° to 5°. 3.4 g of 2-mercaptobenzothiazole and 2.6 g of itaconic acid are then added. After the mixture has been stirred at 20°-25° for 24 hours, the ether solution is poured off and the residue is stirred with 100 ml of water and 100 ml of ethyl acetate. The organic phase is separated off, dried and evaporated. 3 g of 3-(benzothiazol-2-ylthio)-propane-1,2-dicarboxylic acid are obtained as the residue.

후처리

  1. customThe organic phase is separated off
  2. customdried
  3. customevaporated

출처 및 근거

ORD 기록
ord-7b1fd30bd3da47a381b20f84f472db06
출처 데이터셋
uspto-grants-1986_09
특허 번호
US04612378

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