Hydrogen Peroxide → 28893-44-9

HRID 651944

반응식

HRID 651944 반응식
[CH3:1][CH:2]([CH2:4][CH2:5][CH2:6][C@H:7]([C@@H:9]1[C@:26]2([CH3:27])[C@H:12]([C@H:13]3[C@H:23]([CH2:24][CH2:25]2)[C@:21]2([CH3:22])[C:16](=[CH:17][C:18](=[O:28])[CH:19]=[CH:20]2)[CH:15]=[CH:14]3)[CH2:11][CH2:10]1)[CH3:8])[CH3:3].[OH-:29].[Na+].OO>C(O)C>[O:29]1[C@H:19]2[C:18](=[O:28])[CH:17]=[C:16]3[C@:21]([CH3:22])([C@@H:20]12)[C@@H:23]1[C@H:13]([C@H:12]2[C@:26]([CH3:27])([CH2:25][CH2:24]1)[C@@H:9]([C@H:7]([CH3:8])[CH2:6][CH2:5][CH2:4][CH:2]([CH3:1])[CH3:3])[CH2:10][CH2:11]2)[CH:14]=[CH:15]3

참가 물질

5

반응물 3

HCID 784Hydrogen PeroxideHCID 14798Sodium HydroxideHCID 1073901,4,6-Cholestatrien-3-one

생성물 1

HCID 1391110828893-44-9

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

The trienone from (a) (1 gm) in ethanol (50 mls) at 0° was treated with 10% aqueous sodium hydroxide (0.25 ml) and 30% aqueous H2O2 (2.5 ml). The mixture was stored at 5° overnight and then the resulting epoxide was filtered off, washed with aqueous alcohol and dried to afford the title compound (0.86 mgs). Recrystallization from ethanol gave colourless needles, melting point 107°-109°.

후처리

  1. filtrationthe resulting epoxide was filtered off
  2. washwashed with aqueous alcohol
  3. customdried

출처 및 근거

ORD 기록
ord-b723e16e0e7c40a996b359e9ea7317d4
출처 데이터셋
uspto-grants-1987_06
특허 번호
US04670190

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