Acetic Anhydride → 2-(4-Acetoxypiperidino)-5-(2,4-dichlorophenyl)pyrimidine
반응식
[OH:1][CH:2]1[CH2:7][CH2:6][N:5]([C:8]2[N:13]=[CH:12][C:11]([C:14]3[CH:19]=[CH:18][C:17]([Cl:20])=[CH:16][C:15]=3[Cl:21])=[CH:10][N:9]=2)[CH2:4][CH2:3]1.[C:22](OC(=O)C)(=[O:24])[CH3:23]>>[C:22]([O:1][CH:2]1[CH2:3][CH2:4][N:5]([C:8]2[N:9]=[CH:10][C:11]([C:14]3[CH:19]=[CH:18][C:17]([Cl:20])=[CH:16][C:15]=3[Cl:21])=[CH:12][N:13]=2)[CH2:6][CH2:7]1)(=[O:24])[CH3:23]참가 물질
3
실험 절차
6 g of 2-(4-hydroxypiperidino)-5-(2,4-dichlorophenyl)pyrimidine (Example 5) and 60 ml of acetic anhydride are heated under reflux for 4 hours.
후처리
- temperatureunder reflux for 4 hours
출처 및 근거
- ORD 기록
- ord-2f74be5623254999b46f8ab2f9d21007
- 출처 데이터셋
- uspto-grants-1986_09
- 특허 번호
- US04613603
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