Dichloromethane → HCID 20198267, 화합물

HRID 652028

반응식

HRID 652028 반응식
Cl.[CH3:2][Si:3]([CH3:29])([CH3:28])[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][NH:18][C:19]1[CH:27]=[CH:26][C:22]([C:23](Cl)=[O:24])=[CH:21][CH:20]=1.C(Cl)Cl.[OH:33][CH:34]([CH2:39][CH3:40])[C:35]([O:37][CH3:38])=[O:36].C(N(CC)CC)C>CCOCC>[CH3:2][Si:3]([CH3:29])([CH3:28])[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][NH:18][C:19]1[CH:27]=[CH:26][C:22]([C:23]([O:33][CH:34]([C:35]([O:37][CH3:38])=[O:36])[CH2:39][CH3:40])=[O:24])=[CH:21][CH:20]=1

참가 물질

6

반응물 4

HCID 6344DichloromethaneHCID 8471TriethylamineHCID 520445Methyl 2-hydroxybutanoateHCID 20198230HCID 20198230, 화합물

생성물 1

HCID 20198267HCID 20198267, 화합물

시약·촉매·용매 1

HCID 3283Diethyl Ether용매

실험 절차

To a solution of 10.0 g. 4-[14-(trimethylsilyl)tetradecylamino]benzoyl chloride hydrochloride in 200 ml. methylene chloride is added dropwise a solution of 3 g. methyl α-hydroxybutyrate and 5 g. triethylamine in 100 ml. ether. After 17 hours stirring at room temperature, the precipitate is collected and washed with several portions of ether. The ether solution is washed with water, dried and evaporated to yield the product as a white solid.

후처리

  1. customthe precipitate is collected
  2. washwashed with several portions of ether
  3. washThe ether solution is washed with water
  4. customdried
  5. customevaporated

출처 및 근거

ORD 기록
ord-703c8991bd5548c08ffbd47fb47e00ab
출처 데이터셋
uspto-grants-1987_06
특허 번호
US04670421

연결된 노트

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