Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methanesulfonamide → N-[4-[14-(Trimethylsilyl)tetradecylamino]benzoyl]methanesulfonamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methanesulfonamide | HCID 72879 | — |
| 반응물 | 4-[14-(Trimethylsilyl)tetradecylamino]benzoyl chloride hydrochloride | HCID 20198230 | — |
| 용매 | Pyridine | HCID 1049 | — |
| 생성물 | N-[4-[14-(Trimethylsilyl)tetradecylamino]benzoyl]methanesulfonamide | HCID 20198291 | — |
반응 단계
A solution of 12.3 g. of 4-[14-(trimethylsilyl)tetradecylamino]benzoyl chloride hydrochloride and 2.8 g. of methanesulfonamide in 150 ml. of pyridine is stirred at reflux for 2 hours and then evaporated in vacuo. The residue is partitioned between water and diethyl ether, the aqueous layer acidified with 1N hydrochloric acid, and the organic layer separated, dried with magnesium sulfate and evaporated. Crystallization of the residue affords the product as a white solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04670421 |
| 출처 데이터셋 | uspto-grants-1987_06 |
| ORD ID | ord-ae62468ef3c546e7b5459000a2be9856 |
| 출처 메모 | uspto-grants-1987_06 |