Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Trifluoroacetic acid → Ethyl 4-[14-(trimethylsilyl)tetradecylamino]benzoylacetate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Trifluoroacetic acid | HCID 6422 | — |
| 반응물 | Potassium Hydroxide | HCID 14797 | — |
| 반응물 | tert-Butyl ethyl 4-[14-(trimethylsilyl)tetradecylamino]benzoylmalonate | HCID 20198261 | — |
| 생성물 | Ethyl 4-[14-(trimethylsilyl)tetradecylamino]benzoylacetate | HCID 20198260 | — |
반응 단계
A solution of 3.0 g. of tert-butyl ethyl 4-[14-(trimethylsilyl)tetradecylamino]benzoylmalonate and 10 ml. of trifluoroacetic acid is warmed with stirring for 3 hours. The solution is poured onto ice and neutralized with potassium hydroxide. The resulting precipitate is collected by filtration, washed with water and dried. Recrystallization affords the product as a white solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04670421 |
| 출처 데이터셋 | uspto-grants-1987_06 |
| ORD ID | ord-72e4124e5c5e4f489fda6adeebfa3568 |
| 출처 메모 | uspto-grants-1987_06 |