反应详情

A solution of 3.0 g. of tert-butyl ethyl 4-[14-(trimethylsilyl)tetradecylamino]benzoylmalonate and 10 ml. of trifluoroacetic acid is warmed with stirring for 3 hours. The solution is poured onto ice and neutralized with potassium hydroxide. The resulting precipitate is collected by filtration, washed with water and dried. Recrystallization affords the product as a white solid.

1. filtrationThe resulting precipitate is collected by filtration
2. washwashed with water
3. customdried
4. customRecrystallization