참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Tributylphosphine | HCID 13831 | — |
| 반응물 | 2-Propanol, 1,1'-(methylimino)bis- | HCID 95655 | — |
| 촉매 | Ruthenium trichloride | HCID 61850 | — |
| 용매 | Tetraglyme | HCID 8925 | — |
| 생성물 | 2,4,6-Trimethylmorpholine | HCID 19354342 | 90% |
반응 단계
A 300 ml stirred autoclave with pyrex liner was charged a mixture of N-methyldiisopropanolamine (60 g, 0.41 mol), tributylphosphine (1.6 ml), ruthenium trichloride (0.520 g) and tetraglyme (30 ml). The reactor was sealed and purged of air. The reaction was heated to 180° C. and held for three hours. The reaction was allowed to cool to room temperature. The reaction mixtures were distilled to obtain a 90% yield of 2,4,6-trimethylmorpholine.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US04670557 |
|---|
| 출처 데이터셋 | uspto-grants-1987_06 |
|---|
| ORD ID | ord-22b47417fefe45d1b4f5fc0642a392d5 |
|---|
| 출처 메모 | uspto-grants-1987_06 |
|---|
