反应详情

温度

180 °C

A 300 ml stirred autoclave with pyrex liner was charged a mixture of N-methyldiisopropanolamine (60 g, 0.41 mol), tributylphosphine (1.6 ml), ruthenium trichloride (0.520 g) and tetraglyme (30 ml). The reactor was sealed and purged of air. The reaction was heated to 180° C. and held for three hours. The reaction was allowed to cool to room temperature. The reaction mixtures were distilled to obtain a 90% yield of 2,4,6-trimethylmorpholine.

1. additionwas charged
2. customThe reactor was sealed
3. custompurged of air
4. temperatureto cool to room temperature
5. customThe reaction mixtures
6. distillationwere distilled