Thiophenol → 2-[(Phenylsulfanyl)methyl]pentanedinitrile

반응식

[C:1]1([SH:7])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[OH-].[Na+].[CH2:10]=[C:11]([CH2:14][CH2:15][C:16]#[N:17])[C:12]#[N:13]>>[C:1]1([S:7][CH2:10][CH:11]([CH2:14][CH2:15][C:16]#[N:17])[C:12]#[N:13])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

참가 물질

반응물 3

HCID 7969Thiophenol

HCID 14798Sodium Hydroxide

HCID 740802,4-Dicyano-1-butene

생성물 1

HCID 100591792-[(Phenylsulfanyl)methyl]pentanedinitrile

실험 절차

A mixture of thiophenol (3.63 g.), 2N aqueous sodium hydroxide (25 ml.) and 2-methyleneglutaronitrile (3.2 g.) was stirred at room temperature for 18 hours. The mixture was extracted with diethyl ether, and the ether extract washed with water and then dried and evaporated to dryness to give 2-(phenylthiomethyl)glutaronitrile which was used without further purification.