반응식
C(O[CH:5]([N+:11]([O-:13])=[O:12])[CH2:6][CH2:7][CH2:8][CH2:9][CH3:10])(=O)C.C(O[CH:18]([CH2:34][CH2:35][C:36]([C:50]#[N:51])([CH:47]([CH3:49])[CH3:48])[C:37]1[CH:42]=[CH:41][C:40]([O:43][CH3:44])=[C:39]([O:45][CH3:46])[CH:38]=1)[CH:19]([N+:31]([O-:33])=[O:32])[CH2:20][C:21]1[CH:26]=[CH:25][C:24]([O:27][CH3:28])=[C:23]([O:29][CH3:30])[CH:22]=1)(=O)C.[B].[BH4-].[Na+]>>[N+:11]([CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10])([O-:13])=[O:12].[CH3:30][O:29][C:23]1[CH:22]=[C:21]([CH2:20][CH:19]([N+:31]([O-:33])=[O:32])[CH2:18][CH2:34][CH2:35][C:36]([C:50]#[N:51])([CH:47]([CH3:49])[CH3:48])[C:37]2[CH:42]=[CH:41][C:40]([O:43][CH3:44])=[C:39]([O:45][CH3:46])[CH:38]=2)[CH:26]=[CH:25][C:24]=1[O:27][CH3:28]참가 물질
6
반응물 4
생성물 2
실험 절차
The resulting nitrohexanol acetate of formula 9 is then reduced using a boron-based reducing agent, e.g., sodium borohydride, in a 2° or 3° alkanol at 25°-80° C. for 3-15 hours to produce a nitrohexane derivative of formula 10 (step 8). For example, O-acetyl-1-(3,4-dimethoxyphenyl)-2-nitro-6-cyano-6-(i-propyl)-6-(3,4-dimethoxyphenyl)hexan-3-ol (9) is heated with NaBH4 in 2-propanol at reflux for 3-15 hours to yield 1-(3,4-dimethoxyphenyl)-2-nitro-6-cyano-6-(prop-2-yl)-6-(3,4-dimethoxyphenyl)hexane (10).
출처 및 근거
- ORD 기록
- ord-5996a0cb552e4bc3b85ddb845d7c6fa3
- 출처 데이터셋
- uspto-grants-1986_09
- 특허 번호
- US04613606
연결된 노트
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