Toluene → L-Phenylalanine, methyl ester

HRID 65322

반응식

HRID 65322 반응식
[C:1]1(C)C=CC=CC=1.[OH-].[Na+].[NH2:10][C@H:11]([C:19]([OH:21])=[O:20])[CH2:12][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>O>[CH3:1][O:20][C:19](=[O:21])[C@H:11]([CH2:12][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)[NH2:10]

참가 물질

5

반응물 3

HCID 1140TolueneHCID 6140L-PhenylalanineHCID 14798Sodium Hydroxide

생성물 1

HCID 736234L-Phenylalanine, methyl ester

시약·촉매·용매 1

HCID 962Water용매

실험 절차

A 0.2 molar solution phenylalanine methyl ester in 10 milliliters of water was prepared. Toluene was added and the pH of the system adjusted to 7.0 with sodium hydroxide. Chymotrypsin in the amount of 1 milligram was added. The concentration of phenylalanine in the aqueous phase was monitored. The initial concentration was 0.05 molar and the final concentration at the end of the hydrolysis was 0.15 molar, consistent with only one isomer being extracted.

후처리

  1. additionChymotrypsin in the amount of 1 milligram was added
  2. concentrationThe initial concentration was 0.05 molar and the final concentration at the end of the hydrolysis
  3. extractionconsistent with only one isomer being extracted

출처 및 근거

ORD 기록
ord-f97a0b57cff94a51a3997dbb76557cb3
출처 데이터셋
uspto-grants-1986_09
특허 번호
US04613691

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