Hydrochloric Acid → N-[2-[4-(Tetradecyloxy)phenyl]ethyl]-N-[3-(2-thiazolylmethyl)phenyl]acetamide monohydrochloride

HRID 653797노트

반응식

HRID 653797 반응식
[CH2:1]([O:15][C:16]1[CH:21]=[CH:20][C:19]([CH2:22][CH2:23][N:24]([C:28]2[CH:33]=[CH:32][CH:31]=[C:30]([CH2:34][C:35]3[S:36][CH:37]=[CH:38][N:39]=3)[CH:29]=2)[C:25](=[O:27])[CH3:26])=[CH:18][CH:17]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH3:14].[ClH:40]>CCOCC>[ClH:40].[CH2:1]([O:15][C:16]1[CH:17]=[CH:18][C:19]([CH2:22][CH2:23][N:24]([C:28]2[CH:33]=[CH:32][CH:31]=[C:30]([CH2:34][C:35]3[S:36][CH:37]=[CH:38][N:39]=3)[CH:29]=2)[C:25](=[O:27])[CH3:26])=[CH:20][CH:21]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH3:14]

참가 물질

4

반응물 2

HCID 313Hydrochloric AcidHCID 15030169HCID 15030169, 화합물

생성물 1

HCID 19923596N-[2-[4-(Tetradecyloxy)phenyl]ethyl]-N-[3-(2-thiazolylmethyl)phenyl]acetamide monohydrochloride

시약·촉매·용매 1

HCID 3283Diethyl Ether용매2회

실험 절차

To a solution of 300 mg of N-[2-[4-(tetradecyloxy)phenyl]ethyl]-N-[3-(2-thiazolylmethyl)phenyl]acetamide in 3 ml of ether is added 10 ml of ether saturated with hydrogen chloride. The resulting solid is collected by centrifugation, washed several times with ether and vacuum dried to give 200 mg of the desired product, m.p. 114°-118° C.

후처리

  1. customThe resulting solid is collected by centrifugation
  2. washwashed several times with ether and vacuum
  3. customdried

출처 및 근거

ORD 기록
ord-05c4558d4be34814a02d318913e9f810
출처 데이터셋
uspto-grants-1992_07
특허 번호
US05128351

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