Monobasic potassium phosphate → Ribavirin

HRID 65428

반응식

HRID 65428 반응식
[NH:1]1[CH:5]=[N:4][C:3]([C:6]([NH2:8])=[O:7])=[N:2]1.[O:9]=[CH:10][C@@H:11]([C@@H:13]([C@@H:15]([CH2:17][OH:18])[OH:16])[OH:14])O.P([O-])(O)(O)=O.[K+]>>[CH:5]1[N:1]([C@@H:17]2[O:18][C@H:11]([CH2:10][OH:9])[C@@H:13]([OH:14])[C@H:15]2[OH:16])[N:2]=[C:3]([C:6]([NH2:8])=[O:7])[N:4]=1

참가 물질

4

반응물 3

HCID 516951Monobasic potassium phosphateHCID 5311110Aldehydo-D-riboseHCID 178513825HCID 178513825, 화합물

생성물 1

HCID 37542Ribavirin

실험 절차

To each cell suspension was added each 1 ml of an aqueous solution (pH 7.0) containing 20 mM 1,2,4-triazole-3-carboxamide, 20 mM of each of the various ribose donors as shown in Table 3 and 25 mM of monopotassium dihydrogen phosphate, and the reaction was carried out at 60° C. for 24 hours. After completion of the reaction, the cells were removed by centrifugation, and the supernatant was analyzed to obtain the results of ribavirin yield as shown in Table 3.

후처리

  1. customAfter completion of the reaction
  2. customthe cells were removed by centrifugation
  3. customto obtain the

출처 및 근거

ORD 기록
ord-9e8e654260814970a075e1d7bf3a873c
출처 데이터셋
uspto-grants-1986_09
특허 번호
US04614719

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