Acetic Anhydride → HCID 19886039, 화합물

HRID 655051노트

반응식

HRID 655051 반응식
[CH3:1][O:2][C:3]1[CH:37]=[CH:36][C:6]([CH2:7][O:8][C:9]2[CH:10]=[C:11](C(OCC3C=CC=CC=3)(O)C)[CH:12]=[CH:13][C:14]=2[O:15][CH2:16][C:17]2[CH:22]=[CH:21][C:20]([O:23][CH3:24])=[CH:19][CH:18]=2)=[CH:5][CH:4]=1.[C:38](OC(=O)C)(=[O:40])[CH3:39]>N1C=CC=CC=1>[CH3:24][O:23][C:20]1[CH:21]=[CH:22][C:17]([CH2:16][O:15][C:14]2[C:9]([O:8][CH2:7][C:6]3[CH:36]=[CH:37][C:3]([O:2][CH3:1])=[CH:4][CH:5]=3)=[CH:10][CH:11]=[CH:12][C:13]=2[CH:38]([OH:40])[CH3:39])=[CH:18][CH:19]=1

참가 물질

4

반응물 2

HCID 7918Acetic AnhydrideHCID 67742855HCID 67742855, 화합물

생성물 1

HCID 19886039HCID 19886039, 화합물수율 91.5%

시약·촉매·용매 1

HCID 1049Pyridine용매

실험 절차

To an ice cold solution of α-chloro-3,4-dihydroxypropiophenone (2) (1.0 g; 4.98 mMol.) in pyridine (3 ml) is added acetic anhydride (1.2 ml) After 1.5 hours at room temperature, the reaction mixture is concentrated under reduced pressure. The residue is dissolved in chloroform, washed with water, dried, and concentrated under reduced pressure to give α-chloro-2,3-diacetoxypropiopheonen (3) (1.3 g).

후처리

  1. concentrationthe reaction mixture is concentrated under reduced pressure
  2. dissolutionThe residue is dissolved in chloroform
  3. washwashed with water
  4. customdried
  5. concentrationconcentrated under reduced pressure

출처 및 근거

ORD 기록
ord-b20ab1833c8e4b77a941b5b82cc494d5
출처 데이터셋
uspto-grants-1992_07
특허 번호
US05134138

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