5'-Atp → L-Tryptophan

HRID 655094

반응식

HRID 655094 반응식
[CH2:1](OP(O)(O)=O)[C@H:2]1O[C@H:5](OP(OP(O)(O)=O)(O)=O)[C@H:4](O)[C@@H:3]1O.P(OC[C@H]1O[C@@H](N2C3N=CN=C(N)C=3N=C2)[C@H](O)[C@@H]1O)(OP(OP(O)(O)=O)(O)=O)(=O)O.[NH2:54][C@H:55]([C:62]([OH:64])=[O:63])[CH2:56][C:57]1N=[CH:60][NH:59][CH:58]=1>>[NH2:54][C@H:55]([C:62]([OH:64])=[O:63])[CH2:56][C:57]1[C:5]2[C:60](=[CH:1][CH:2]=[CH:3][CH:4]=2)[NH:59][CH:58]=1

참가 물질

4

반응물 3

HCID 59575'-Atp2회HCID 7339Phosphoribosyl Pyrophosphate2회HCID 178419078HCID 178419078, 화합물2회

생성물 1

HCID 6305L-Tryptophan

실험 절차

5-Phosphoribosyl-α-1-pyrophosphate (hereinafter, “PRPP”) and adenosine-5′-triphosphate (hereinafter, “ATP”) are the initial substrates in histidine biosynthesis. PRPP can sometimes induce the histidine biosynthesis to follow divergent pathways, resulting in the biosynthesis of pyrimidine nucleotides, purine nucleotides, pyridine nucleotides, and tryptophan (Escherichia coli and Salmonella, Second Edition, Editor in Chief: F. C. Neidhardt, ASM Press, Washington D.C., 1996).

출처 및 근거

ORD 기록
ord-8a93aaca8cfb4bda82219c51c57b8cd5
출처 데이터셋
uspto-grants-2011_12
특허 번호
US08071339B2

연결된 노트

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