phenylalaninol, (S)- → (2R,3R,4S,5R)-2-[6-((S)-1-Benzyl-2-hydroxyethylamino)-2-chloro-purin-9-yl]-5-(2-benzyl-2H-tetrazol-5-yl)-tetrahydro-furan-3,4-diol

참여 물질

역할	이름	HCID	투입량
반응물	phenylalaninol, (S)-	HCID 447213	—
반응물	(2R,3S,4R,5R)-2-(2-benzyl-2H-tetrazol-5-yl)-5-[2-chloro-6-(2,2-diphenyl-ethylamino)-purin-9-yl]-tetrahydro-furan-3,4-diol	HCID 86645702	—
생성물	(2R,3R,4S,5R)-2-[6-((S)-1-Benzyl-2-hydroxyethylamino)-2-chloro-purin-9-yl]-5-(2-benzyl-2H-tetrazol-5-yl)-tetrahydro-furan-3,4-diol	HCID 86645701	—

반응 단계

The title compound is prepared in an analogous fashion to (2R,3S,4R,5R)-2-(2-benzyl-2H-tetrazol-5-yl)-5-[2-chloro-6-(2,2-diphenylethylamino)-purin-9-yl]-tetrahydro-furan-3,4-diol (WO 99/38877) by replacing 2,2-diphenylethylamine with (S)-2-amino-3-phenyl-propan-1-ol

출처 및 근거

DOI	10.6084/m9.figshare.5104873.v1
특허 번호	US08071565B2
출처 데이터셋	uspto-grants-2011_12
ORD ID	ord-3c269b48a2f8459f96d619355dd99ad8
출처 메모	uspto-grants-2011_12