Hydrochloric Acid → HCID 68820112, 화합물
반응식
C(OC([N:8]([C:10]1[CH:15]=[CH:14][C:13]([N:16]2[CH:20]=[CH:19][CH:18]=[CH:17]2)=[CH:12][CH:11]=1)[NH2:9])=O)(C)(C)C.O1CCOCC1.[ClH:27]>C(Cl)Cl>[ClH:27].[N:16]1([C:13]2[CH:14]=[CH:15][C:10]([NH:8][NH2:9])=[CH:11][CH:12]=2)[CH:17]=[CH:18][CH:19]=[CH:20]1참가 물질
5
실험 절차
Title compound 50A, N-(4-Pyrrol-1-yl-phenyl)-hydrazinecarboxylic acid tert-butyl ester (0.32 g, 1.0 eq, 1.2 mmol) was suspended in a mixture of 4M HCl in Dioxane (4.9 ml, 17.0 eq, 19.7 mmol) and DCM (5 ml). The mixture was then stirred at room temperature for 24 hr solvent was then removed in vacuo to yield the title compound as an off-white solid (0.25 g, 1.12 mmol, 95%). LCMS: [M+H]+=157/174, rt=0.98 min, 98% purity.
후처리
- customwas then removed in vacuo
출처 및 근거
- ORD 기록
- ord-77fad973892549f29eba5e7eff08c500
- 출처 데이터셋
- uspto-grants-2011_12
- 특허 번호
- US08071607B2
반응 노트
불러오는 중…