4-Methoxy-2,5-dimethylbenzaldehyde → Tetrahydro-3,5-bis[(4-methoxy-2,5-dimethylphenyl)methylene]-4H-pyran-4-one

HRID 65676노트

반응식

HRID 65676 반응식
[O:1]1[CH2:6][CH2:5][C:4](=[O:7])[CH2:3][CH2:2]1.[CH3:8][C:9]1[CH:16]=[C:15]([O:17][CH3:18])[C:14]([CH3:19])=[CH:13][C:10]=1[CH:11]=O>CCO.Cl>[CH3:18][O:17][C:15]1[C:14]([CH3:19])=[CH:13][C:10]([CH:11]=[C:3]2[C:4](=[O:7])[C:5](=[CH:11][C:10]3[CH:13]=[C:14]([CH3:19])[C:15]([O:17][CH3:18])=[CH:16][C:9]=3[CH3:8])[CH2:6][O:1][CH2:2]2)=[C:9]([CH3:8])[CH:16]=1

참가 물질

5

반응물 2

HCID 812274-Methoxy-2,5-dimethylbenzaldehydeHCID 121599Tetrahydro-4H-pyran-4-one

생성물 1

HCID 53782418Tetrahydro-3,5-bis[(4-methoxy-2,5-dimethylphenyl)methylene]-4H-pyran-4-one수율 39%

시약·촉매·용매 2

HCID 313Hydrochloric Acid용매HCID 702Ethanol용매

실험 절차

A solution of 7.0 g (0.07 mole) of tetrahydro-4H-pyran-4-one and 25.2 g (0.15 mole) of 2,5-dimethyl-p-anisaldehyde in 75 ml of EtOH and 10 ml of concentrated HCl is stirred and heated at reflux for 3 hours. The resulting mixture is kept at room temperature for 24 hours, yielding 10.7 g (39%) of yellow solid, m.p. 182°-184°.

후처리

  1. temperatureheated
  2. temperatureat reflux for 3 hours

출처 및 근거

ORD 기록
ord-0a4a7c4dad0e4517b7741b4e2356127b
출처 데이터셋
uspto-grants-1978_12
특허 번호
US04128648

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