tert-BUTYL CHLORIDE → Pyrene, 1-(1,1-dimethylethyl)-

HRID 656848

반응식

HRID 656848 반응식
[CH:1]1[C:14]2[C:15]3=[C:16]4[C:11](=[CH:12][CH:13]=2)[CH:10]=[CH:9][CH:8]=[C:7]4[CH:6]=[CH:5][C:4]3=[CH:3][CH:2]=1.[C:17](Cl)([CH3:20])([CH3:19])[CH3:18].[Cl-].[Al+3].[Cl-].[Cl-]>C(Cl)Cl.O>[C:17]([C:8]1[C:7]2[C:16]3=[C:15]4[C:4](=[CH:5][CH:6]=2)[CH:3]=[CH:2][CH:1]=[C:14]4[CH:13]=[CH:12][C:11]3=[CH:10][CH:9]=1)([CH3:20])([CH3:19])[CH3:18]

참가 물질

6

반응물 3

HCID 10486tert-BUTYL CHLORIDEHCID 31423PyreneHCID 6451240Aluminum(III) Chloride

생성물 1

HCID 187956Pyrene, 1-(1,1-dimethylethyl)-수율 51.1%

시약·촉매·용매 2

HCID 962Water용매HCID 6344Dichloromethane용매2회

반응 조건

온도
0 °C

실험 절차

In a reaction vessel, 50.0 g (0.25 mol) of pyrene, 27.6 g (0.30 mol) of tert-butyl chloride, and 200 ml of methylene chloride were charged, and the resulting mixture was cooled to 0° C. Next, 35.3 g (0.27 mol) of aluminum chloride was charged, followed by stirring at room temperature for 2 hours. Then, iced water and methylene chloride were added, and an organic layer was extracted, washed with water, dried over magnesium sulfate, and recrystallized to produce 33 g of tert-butylpyrene crystals in a yield of 51%.

후처리

  1. extractionan organic layer was extracted
  2. washwashed with water
  3. dry with materialdried over magnesium sulfate
  4. customrecrystallized

출처 및 근거

ORD 기록
ord-c1dab17752ad443b8a4feaa787b65f85
출처 데이터셋
uspto-grants-2011_12
특허 번호
US08071993B2

연결된 노트

불러오는 중…