Piperonyl alcohol → 1,3-Benzodioxole, 5-(chloromethyl)-

HRID 65699

반응식

HRID 65699 반응식
S(Cl)([Cl:3])=O.[CH2:5]1[O:15][C:14]2[CH:13]=[CH:12][C:9]([CH2:10]O)=[CH:8][C:7]=2[O:6]1>>[CH2:5]1[O:15][C:14]2[CH:13]=[CH:12][C:9]([CH2:10][Cl:3])=[CH:8][C:7]=2[O:6]1

참가 물질

3

반응물 2

HCID 10322Piperonyl alcoholHCID 24386Thionyl Chloride

생성물 1

HCID 887131,3-Benzodioxole, 5-(chloromethyl)-

실험 절차

153.9 g (1.29 mols) of thionyl chloride are poured onto 65.6 g (0.431 mol) of 3,4-methylenedioxybenzyl alcohol. The mixture is stirred for 90 minutes at ambient temperature (15°-25° C.) and the excess thionyl chloride is then evaporated. The residue is taken up in dimethylformainde (DMF) and the latter is then evaporated. Finally, the residue is taken up in 500 ml of DMF (it is not necessary to isolate the 3,4-methylenedioxybenzyl chloride thus obtained).

후처리

  1. customthe excess thionyl chloride is then evaporated
  2. customthe latter is then evaporated

출처 및 근거

ORD 기록
ord-6894a54152924af49879deb8373082ee
출처 데이터셋
uspto-grants-1978_12
특허 번호
US04128656

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