Acetic Anhydride → 3-Methoxycarbonyl-2-benzylidenepropanoic acid

HRID 65715노트

반응식

HRID 65715 반응식
[C:1]([CH2:4][C:5](=[CH:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)[C:6]([OH:8])=[O:7])([OH:3])=[O:2].[C:16](OC(=O)C)(=O)C>>[CH3:16][O:2][C:1]([CH2:4][C:5](=[CH:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)[C:6]([OH:8])=[O:7])=[O:3]

참가 물질

3

반응물 2

HCID 7918Acetic AnhydrideHCID 2229982-(Phenylmethylene)butanedioic acid

생성물 1

HCID 541581613-Methoxycarbonyl-2-benzylidenepropanoic acid

실험 절차

2-Carboxymethyl-3-phenylpropenoic acid (4.1 g.) and acetic anhydride (9 ml.) are heated in the steam bath for 70 minutes. The mixture is concentrated to dryness and the residue triturated with ether, yield 3.6 g. This anhydride is dissolved in 7 ml. of methanol and heated in the steam bath for 1 hour.

후처리

  1. concentrationThe mixture is concentrated to dryness
  2. customthe residue triturated with ether, yield 3.6 g
  3. dissolutionThis anhydride is dissolved in 7 ml
  4. temperatureof methanol and heated in the steam bath for 1 hour

출처 및 근거

ORD 기록
ord-4a01dc0b015e4df892b58a99116b9e01
출처 데이터셋
uspto-grants-1978_12
특허 번호
US04128653

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