Pyrrolidine → 5-Nitro-2-pyrrolidin-1-yl-pyrimidine

HRID 657253

반응식

HRID 657253 반응식
Cl[C:2]1[N:7]=[CH:6][C:5]([N+:8]([O-:10])=[O:9])=[CH:4][N:3]=1.[NH:11]1[CH2:15][CH2:14][CH2:13][CH2:12]1>>[N+:8]([C:5]1[CH:4]=[N:3][C:2]([N:11]2[CH2:15][CH2:14][CH2:13][CH2:12]2)=[N:7][CH:6]=1)([O-:10])=[O:9]

참가 물질

3

반응물 2

HCID 31268PyrrolidineHCID 825442-Chloro-5-nitropyrimidine

생성물 1

HCID 587706385-Nitro-2-pyrrolidin-1-yl-pyrimidine

실험 절차

Prepared essentially as described in Example 69a, using 2-chloro-5-nitro-pyrimidine and pyrrolidine. 1H NMR (DMSO-d6) δ 9.11 (s, 2H), 3.62 (m, 4H), 1.97 (m, 4H).

후처리

  1. customPrepared essentially

출처 및 근거

ORD 기록
ord-6e1f95824d2c43d08e815127e2bf7f25
출처 데이터셋
uspto-grants-2011_12
특허 번호
US08071768B2

연결된 노트

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