Acetic Acid → 2-Cyclohexen-1-one, 2,5,6-trimethyl-

HRID 65801

반응식

HRID 65801 반응식
[CH:1](=[O:5])/[CH:2]=[CH:3]/[CH3:4].[CH2:6]([C:8]([CH2:10]C)=O)[CH3:7].C[O-].[Na+].[C:15](O)(=O)C>CO>[CH3:15][C:2]1[C:1](=[O:5])[CH:6]([CH3:7])[CH:8]([CH3:10])[CH2:4][CH:3]=1

참가 물질

6

반응물 4

HCID 176Acetic AcidHCID 7288Ethyl ketoneHCID 447466CrotonaldehydeHCID 10942334Sodium Methoxide

생성물 1

HCID 892642-Cyclohexen-1-one, 2,5,6-trimethyl-

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

70 g of crotonaldehyde is dripped in the course of one hour into a mixture of 400 g of diethyl ketone and 10 g of a 30% solution of sodium methylate in methanol which is boiling under reflux and the reaction mixture is boiled for another half hour under reflux. The whole is neutralized with glacial acetic acid and the mixture obtained is filtered. 325 g of diethyl ketone is recovered by distillation of the filtrate; 55 g of 2,5,6-trimethyl-2-cyclohexen-1-one having a boiling point of from 74° to 76° C. at 12 mm Hg is obtained. The yield with reference to crotonaldehyde is 40%.

후처리

  1. temperatureunder reflux
  2. temperatureunder reflux
  3. customthe mixture obtained
  4. filtrationis filtered
  5. distillation325 g of diethyl ketone is recovered by distillation of the filtrate

출처 및 근거

ORD 기록
ord-8d2ac9117a644f9d8f308d3ba69ae5b1
출처 데이터셋
uspto-grants-1978_12
특허 번호
US04128728

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