Allyl bromide → N-[4-(Allylsulfonyl)phenyl]acetamide

HRID 65836

반응식

HRID 65836 반응식
[C:1]([NH:4][C:5]1[CH:10]=[CH:9][C:8]([S:11]([OH:13])=[O:12])=[CH:7][CH:6]=1)(=[O:3])[CH3:2].C(=O)([O-])O.[Na+].[CH2:19](Br)[CH:20]=[CH2:21]>O>[CH2:21]([S:11]([C:8]1[CH:7]=[CH:6][C:5]([NH:4][C:1](=[O:3])[CH3:2])=[CH:10][CH:9]=1)(=[O:13])=[O:12])[CH:20]=[CH2:19]

참가 물질

5

반응물 3

HCID 7841Allyl bromideHCID 4121504-(Acetylamino)benzenesulfinic acidHCID 516892Sodium Bicarbonate

생성물 1

HCID 20375362N-[4-(Allylsulfonyl)phenyl]acetamide

시약·촉매·용매 1

HCID 962Water용매

실험 절차

50 Parts of p-acetylaminophenylsulfinic acid and 25 parts of sodium hydrogen carbonate are suspended in 300 parts of water. While stirring intensely 36 parts of allyl bromide is dripped in within 3 hours at 50° to 60° C. Stirring is continued for another 4 hours at 60° C. 45 parts of p-allylsulfonylacetanilide is obtained with a melting point of 116° to 118° C.

후처리

  1. customis dripped in within 3 hours at 50° to 60° C

출처 및 근거

ORD 기록
ord-b7eadcc681184887b4d6356783e873da
출처 데이터셋
uspto-grants-1978_12
특허 번호
US04129563

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