Phosgene → Dimethyl terephthalate

HRID 65885

반응식

HRID 65885 반응식
[C:1]([OH:12])(=[O:11])[C:2]1[CH:10]=[CH:9][C:5]([C:6]([OH:8])=O)=[CH:4][CH:3]=1.[CH3:13]C1C=CN=CC=1.[C:20](Cl)(Cl)=[O:21].CC1C=CC=CN=1.C(Cl)(=O)C1C=CC(C(Cl)=O)=CC=1>ClCCl>[C:6]([O:21][CH3:20])(=[O:8])[C:5]1[CH:4]=[CH:3][C:2]([C:1]([O:12][CH3:13])=[O:11])=[CH:10][CH:9]=1

참가 물질

7

반응물 5

HCID 6371PhosgeneHCID 7488Terephthaloyl chlorideHCID 7489Terephthalic AcidHCID 79634-MethylpyridineHCID 79752-Methylpyridine

생성물 1

HCID 8441Dimethyl terephthalate수율 100%

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

Following the general procedure of Example 1 for the preparation of the diacid chloride, 9.06 parts of terephthalic acid were added to a mixture of 11.82 parts of 4-methylpyridine and 14.1 parts phosgene in 200 parts dry dichloromethane at 25° to 30° C. The ratio of equivalents of methylpyridine base/COOH acid group was 1.16. After carrying out the reaction and esterifying the resulting diacid chloride by the procedure described in Example 1, a 100% yield of dimethyl terephthalate was obtained corresponding to a quantitive yield of terephthaloyl chloride formed initially in the reaction.

후처리

  1. customthe reaction

출처 및 근거

ORD 기록
ord-99098360bf6e490090e32b54db424b8d
출처 데이터셋
uspto-grants-1978_12
특허 번호
US04129594

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