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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 659530생성일: 2026년 10월 25일

3-(Pyrrolidin-2-yl)pyridine → (3-{1-[5-Chloro-2-(trifluoromethyl)benzyl]-1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-7-yl}phenyl)-(2-pyridin-3-ylpyrrolidin-1-yl)methanone

https://huagongshe.com/reaction/659530

반응식

참여 물질

역할이름HCID투입량
반응물3-(Pyrrolidin-2-yl)pyridineHCID 412—
반응물3-{1-[5-Chloro-2-(trifluoromethyl)benzyl]-1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-7-yl}benzoic acidHCID 58327807—
생성물(3-{1-[5-Chloro-2-(trifluoromethyl)benzyl]-1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-7-yl}phenyl)-(2-pyridin-3-ylpyrrolidin-1-yl)methanoneHCID 58327923—

반응 단계

3-{1-[5-chloro-2-(trifluoromethyl)benzyl]-1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-7-yl}benzoic acid was reacted with 2-(3-pyridinyl)pyrrolidine as in General Procedure 10 to give the title compound. LCMS: m/z=577.95 (M+H+); retention time=0.65 minutes.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08080561B2
출처 데이터셋uspto-grants-2011_12
ORD IDord-42a6c698b24248e8a70cfce0b7deffd1
출처 메모uspto-grants-2011_12