NADPH → (S)-1-(3,4-Dimethoxyphenyl)propan-2-OL

HRID 6600

반응식

HRID 6600 반응식
C1N=C(N)C2N=CN([C@@H]3O[C@H](COP(OP(OC[C@H]4O[C@@H](N5C=C(C(N)=O)CC=C5)[C@H](O)[C@@H]4O)(O)=O)(O)=O)[C@@H](O)[C@H]3OP(O)(O)=O)C=2N=1.[CH3:49][O:50][C:51]1[CH:52]=[C:53]([CH2:59][C:60](=[O:62])[CH3:61])[CH:54]=[CH:55][C:56]=1[O:57][CH3:58]>>[CH3:49][O:50][C:51]1[CH:52]=[C:53]([CH2:59][C@@H:60]([OH:62])[CH3:61])[CH:54]=[CH:55][C:56]=1[O:57][CH3:58]

참가 물질

3

반응물 2

HCID 5884NADPH2회HCID 698962-Propanone, 1-(3,4-dimethoxyphenyl)-

생성물 1

HCID 10198066(S)-1-(3,4-Dimethoxyphenyl)propan-2-OL

실험 절차

The carbonyl reductases of the present invention can utilize NADPH as a coenzyme, have no alcohol dehydrogenating activity, and reduce 3,4-dimethoxyphenylacetone by utilizing NADPH as a coenzyme to produce 90% ee or more (S)-1-(3,4-dimethoxyphenyl)-2-propanol.

출처 및 근거

ORD 기록
ord-9738564159bc4fc6bc633e268b9088a2
출처 데이터셋
uspto-grants-2006_08
특허 번호
US07083962B2

연결된 노트

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