Benzoyl Peroxide → Ethyl 2-bromo-2-(3,4-dichlorophenyl)acetate

HRID 66285

반응식

HRID 66285 반응식
[Cl:1][C:2]1[CH:3]=[C:4]([CH2:9][C:10]([O:12][CH2:13][CH3:14])=[O:11])[CH:5]=[CH:6][C:7]=1[Cl:8].[Br:15]N1C(=O)CCC1=O.C(OOC(=O)C1C=CC=CC=1)(=O)C1C=CC=CC=1>C(Cl)(Cl)(Cl)Cl>[Br:15][CH:9]([C:4]1[CH:5]=[CH:6][C:7]([Cl:8])=[C:2]([Cl:1])[CH:3]=1)[C:10]([O:12][CH2:13][CH3:14])=[O:11]

참가 물질

5

반응물 3

HCID 7187Benzoyl PeroxideHCID 67184N-bromobutanimideHCID 2737422Ethyl 3,4-dichlorophenylacetate

생성물 1

HCID 12717583Ethyl 2-bromo-2-(3,4-dichlorophenyl)acetate

시약·촉매·용매 1

HCID 5943Carbon Tetrachloride용매

실험 절차

In a three-necked flask fitted with a Nichrome stirrer and a reflux condenser is placed 7.0 g of ethyl 3,4-dichlorophenylacetate, 5.9 g of N-bromosuccinimide, 0.1 g of benzoyl peroxide and 150 ml of carbon tetrachloride. The reaction mixture is heated at reflux for 18 hours, cooled and filtered. The carbon tetrachloride filtrate is concentrated under reduced pressure to give a deep orange liquid. Vacuum distillation at 115°-120° C. (0.5 mm) gives ethyl α-bromo-3,4-dichlorophenylacetate as a pale yellow liquid.

후처리

  1. customIn a three-necked flask fitted with a Nichrome stirrer and a reflux condenser
  2. temperatureThe reaction mixture is heated
  3. temperatureat reflux for 18 hours
  4. temperaturecooled
  5. filtrationfiltered
  6. concentrationThe carbon tetrachloride filtrate is concentrated under reduced pressure
  7. customto give a deep orange liquid
  8. distillationVacuum distillation at 115°-120° C. (0.5 mm)

출처 및 근거

ORD 기록
ord-8bb4d254d7f440ec8351d60f1eca7e2b
출처 데이터셋
uspto-grants-1978_12
특허 번호
US04131611

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