2,3-Dichloropyrazine → 2-Chloro-3-phenoxypyrazine

반응식

[O-:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[Na+].[Cl:9][C:10]1[C:15](Cl)=[N:14][CH:13]=[CH:12][N:11]=1>>[Cl:9][C:10]1[C:15]([O:1][C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=2)=[N:14][CH:13]=[CH:12][N:11]=1

참가 물질

반응물 2

HCID 785752,3-Dichloropyrazine

HCID 4445035Phenolate Sodium

생성물 1

HCID 205289612-Chloro-3-phenoxypyrazine

실험 절차

A suspension of 0.1 mole of sodium phenoxide and 0.1 mole, 2,3-dichloropyrazine is refluxed 10-20 hours. The cooled mixture is extracted with diethyl ether, washed with cold 2 N sodium hydroxide solution, dried, and evaporated to give 2-chloro-3-phenoxypyrazine.

후처리

temperatureis refluxed 10-20 hours
extractionThe cooled mixture is extracted with diethyl ether
washwashed with cold 2 N sodium hydroxide solution
customdried
customevaporated

출처 및 근거

ORD 기록: ord-d1e4ba00ec704ab99e6cf8689a469efc
출처 데이터셋: uspto-grants-1982_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04343802

반응 노트

불러오는 중…