Hydrochloric Acid → 2-Methyl-2-[3-methyl-1-propyl-2-(4-pyridyl)-1H-indole-5-yloxy]propanoic acid hydrochloride

HRID 66888노트

반응식

HRID 66888 반응식
C([O:3][C:4](=[O:28])[C:5]([CH3:27])([O:7][C:8]1[CH:9]=[C:10]2[C:14](=[CH:15][CH:16]=1)[N:13]([CH2:17][CH2:18][CH3:19])[C:12]([C:20]1[CH:25]=[CH:24][N:23]=[CH:22][CH:21]=1)=[C:11]2[CH3:26])[CH3:6])C.[ClH:29]>>[ClH:29].[CH3:6][C:5]([O:7][C:8]1[CH:9]=[C:10]2[C:14](=[CH:15][CH:16]=1)[N:13]([CH2:17][CH2:18][CH3:19])[C:12]([C:20]1[CH:25]=[CH:24][N:23]=[CH:22][CH:21]=1)=[C:11]2[CH3:26])([CH3:27])[C:4]([OH:28])=[O:3]

참가 물질

3

반응물 2

HCID 313Hydrochloric AcidHCID 538957452-methyl-2-[3-methyl-1-propyl-2-(4-pyridyl)-1H-indole-5-yloxy]propanoic acid ethylester

생성물 1

HCID 705486392-Methyl-2-[3-methyl-1-propyl-2-(4-pyridyl)-1H-indole-5-yloxy]propanoic acid hydrochloride

실험 절차

The above compound was prepared from 2-methyl-2-[3-methyl-1-propyl-2-(4-pyridyl)-1H-indole-5-yloxy]propanoic acid ethylester by hydrolysis with diluted hydrochloric acid at the boiling temperature. After the hydrochloric acid was distilled off in vacuo, the reaction product was recrystallized from acetone.

후처리

  1. distillationAfter the hydrochloric acid was distilled off in vacuo
  2. customthe reaction product was recrystallized from acetone

출처 및 근거

ORD 기록
ord-406739993b464f6e85a11eda7de205f7
출처 데이터셋
uspto-grants-1982_08
특허 번호
US04343811

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