Potassium Permanganate → 1-Ethyl-5-butyryl-6-methyl-benzimidazole-2-carboxylic acid

HRID 67147노트

반응식

HRID 67147 반응식
[CH2:1]([N:3]1[C:7]2[CH:8]=[C:9]([CH3:17])[C:10]([C:12](=[O:16])[CH2:13][CH2:14][CH3:15])=[CH:11][C:6]=2[N:5]=[C:4]1[CH2:18][OH:19])[CH3:2].[Mn]([O-])(=O)(=O)=[O:21].[K+]>>[CH2:1]([N:3]1[C:7]2[CH:8]=[C:9]([CH3:17])[C:10]([C:12](=[O:16])[CH2:13][CH2:14][CH3:15])=[CH:11][C:6]=2[N:5]=[C:4]1[C:18]([OH:21])=[O:19])[CH3:2]

참가 물질

3

반응물 2

HCID 516875Potassium PermanganateHCID 130606811-Ethyl-5-butyryl-6-methyl-benzimidazole-2-methanol

생성물 1

HCID 128066581-Ethyl-5-butyryl-6-methyl-benzimidazole-2-carboxylic acid

실험 절차

In a manner analogous to that described in Example 12, 5.2 g of 1-ethyl-5-butyryl-6-methyl-benzimidazole-2-methanol can be oxidised with 4.5 g of potassium permanganate to give 1-ethyl-5-butyryl-6-methyl-benzimidazole-2-carboxylic acid with a melting point >80° (decomposition).

출처 및 근거

ORD 기록
ord-5b4385fbd1a1402297d6cadd0c844878
출처 데이터셋
uspto-grants-1982_08
특허 번호
US04344957

반응 노트

불러오는 중…