3-Nitro-p-cresol → 3-Amino-p-cresol
반응식
[N+:1]([C:4]1[CH:5]=[C:6]([OH:11])[CH:7]=[CH:8][C:9]=1[CH3:10])([O-])=O.[H][H]>[Ni].O1CCCC1>[NH2:1][C:4]1[CH:5]=[C:6]([OH:11])[CH:7]=[CH:8][C:9]=1[CH3:10]참가 물질
5
실험 절차
70 g of 3-nitro-4-methylphenol, prepared according to German Offenalegungschrift No. 2,213,568, 200 ml of tetrahydrofuran and 2 g of activated Raney nickel catalyst were placed in a Parr bomb. The mixture was shaken for 3.5 hours under 60 p.s.i. hydrogen pressure. The mixture then was filtered and the solvent was evaporated from the filtrate. The residue was recrystallized from ether to give 3-amino-4-methylphenol (3A), as a grey solid, mp: 145°-148° C.
후처리
- filtrationThe mixture then was filtered
- customthe solvent was evaporated from the filtrate
- customThe residue was recrystallized from ether
출처 및 근거
- ORD 기록
- ord-2a417ce8477b47ffb0400faad8e9f2d7
- 출처 데이터셋
- uspto-grants-1982_08
- 특허 번호
- US04345077
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