Ammonium → 5'-O-tert-ButyldimethylsilylRosuvastatinLactone

HRID 671961

반응식

[C:54]([CH3:55])([CH3:56])([CH3:57])[Si:58]([O:59][CH:60]1[CH2:61][CH:62]([CH:67]=[O:68])[O:63][C:64](=[O:66])[CH2:65]1)([CH3:69])[CH3:70].[CH3:44][SiH:45]([CH3:46])[N:47]([CH3:48])[Si:49]([CH3:50])([CH3:51])[CH3:52].[CH3:73][c:74]1[cH:75][cH:76][cH:77][cH:78][cH:79]1.[Cl-:71].[F:1][C:2]([F:3])([F:4])[C:5]([O-:6])=[O:7].[F:8][c:9]1[cH:10][cH:11][c:12](-[c:15]2[n:16][c:17]([N:38]([S:39](=[O:40])(=[O:41])[CH3:42])[CH3:43])[n:18][c:19]([CH:35]([CH3:36])[CH3:37])[c:20]2[CH2:21][P+:22]([CH2:23][CH2:24][CH2:25][CH3:26])([CH2:27][CH2:28][CH2:29][CH3:30])[CH2:31][CH2:32][CH2:33][CH3:34])[cH:13][cH:14]1.[NH4+:72].[Na:53].[OH2:80]>>[F:8][c:9]1[cH:10][cH:11][c:12](-[c:15]2[n:16][c:17]([N:38]([S:39](=[O:40])(=[O:41])[CH3:42])[CH3:43])[n:18][c:19]([CH:35]([CH3:36])[CH3:37])[c:20]2[CH:21]=[CH:67][CH:62]2[CH2:61][CH:60]([O:59][Si:58]([C:54]([CH3:55])([CH3:56])[CH3:57])([CH3:69])[CH3:70])[CH2:65][C:64](=[O:66])[O:63]2)[cH:13][cH:14]1