Ethyl bromoacetate → 3-Methyl-4-oxo-2-phenyliminothiazolidine hydrobromide

HRID 67782

반응식

HRID 67782 반응식
[Br:1]CC([O:5][CH2:6][CH3:7])=O.[CH3:8][NH:9][C:10]([NH:12][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)=[S:11]>CC(C)=O>[BrH:1].[CH3:8][N:9]1[C:6](=[O:5])[CH2:7][S:11][C:10]1=[N:12][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1

참가 물질

4

반응물 2

HCID 7748Ethyl bromoacetateHCID 6982941-Methyl-3-phenylthiourea

생성물 1

HCID 205271953-Methyl-4-oxo-2-phenyliminothiazolidine hydrobromide

시약·촉매·용매 1

HCID 180Acetone용매

실험 절차

10 g of ethyl bromoacetate and 9.95 g of 1-methyl-3-phenylthiourea in 150 ml of acetone are boiled for 1 hour under a reflux condenser. The reaction mixture is allowed to cool and the crystals are filtered off and washed with acetone. Melting point 212°-215° C.

후처리

  1. temperatureto cool
  2. filtrationthe crystals are filtered off
  3. washwashed with acetone

출처 및 근거

ORD 기록
ord-807f3c22deb64f20afe079763f77af03
출처 데이터셋
uspto-grants-1982_08
특허 번호
US04346088

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