1,3-Dichloroacetone → HCID 86736622, 화합물

HRID 67984노트

반응식

HRID 67984 반응식
[Cl:1][CH2:2][C:3]([CH2:5]Cl)=O.[CH2:7]([NH:11][C:12]([NH:14][C:15]([NH2:17])=[S:16])=[NH:13])[CH2:8][CH2:9][CH3:10]>CC(C)=O>[ClH:1].[CH2:7]([N:11]=[C:12]([NH2:13])[NH:14][C:15]1[S:16][CH:5]=[C:3]([CH2:2][Cl:1])[N:17]=1)[CH2:8][CH2:9][CH3:10]

참가 물질

4

반응물 2

HCID 107931,3-DichloroacetoneHCID 178449223HCID 178449223, 화합물

생성물 1

HCID 86736622HCID 86736622, 화합물

시약·촉매·용매 1

HCID 180Acetone용매2회

실험 절차

A solution of 1,3-dichloroacetone (3.02 g.) in acetone (10 ml.) was added to a stirred suspension of (N-n-butylamidino)thiourea (4.04 g.) in acetone (25 ml.) at room temperature. The resulting clear pale yellow solution was stirred for three days, then cooled in ice, and the precipitated solid filtered off and washed with acetone to give 2-(2-n-butylguanidino)-4-chloromethylthiazole hydrochloride.

후처리

  1. temperaturecooled in ice
  2. filtrationthe precipitated solid filtered off
  3. washwashed with acetone

출처 및 근거

ORD 기록
ord-0019d0ab90104c68a6748b211f055de3
출처 데이터셋
uspto-grants-1982_08
특허 번호
US04347370

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