Mannitol → Oxycodone

HRID 68197

반응식

[CH3:1][N:2]1[C@@H:19]2[CH2:20][C:7]3[CH:8]=[CH:9][C:10]([O:22][CH3:23])=[C:11]4[O:12][C@H:13]5[C:14]([CH2:16][CH2:17][C@:18]2([OH:21])[C@:5]5([C:6]=34)[CH2:4][CH2:3]1)=[O:15].Cl.C(O)[C@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O>>[CH3:1][N:2]1[C@@H:19]2[CH2:20][C:7]3[CH:8]=[CH:9][C:10]([O:22][CH3:23])=[C:11]4[O:12][C@H:13]5[C:14]([CH2:16][CH2:17][C@:18]2([OH:21])[C@:5]5([C:6]=34)[CH2:4][CH2:3]1)=[O:15]

참가 물질

반응물 2

HCID 6251Mannitol

HCID 5462350Oxycodone Hydrochloride

생성물 1

HCID 5284603Oxycodone

실험 절차

The active plug comprised: Oxycodone hydrochloride, PEO 200 000, Mannitol, PoloXamer 407, which were mixed. Afterwards the powder mixture fed to the injection moulding machine.

출처 및 근거

ORD 기록: ord-e5cb8d78f176464f9c29e2d601fe3958
출처 데이터셋: uspto-grants-2014_09
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08821928B2

연결된 노트

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