4-(Bromomethyl)oxane → HCID 57916900, 화합물

HRID 69526

반응식

HRID 69526 반응식
[N:1]1([C@@H:6]2[CH2:10][CH2:9][N:8]([C:11]3[CH:16]=[CH:15][C:14]([N:17]4[CH:26]=[CH:25][C:24]5[C:19](=[CH:20][CH:21]=[C:22]([OH:27])[CH:23]=5)[C:18]4=[O:28])=[CH:13][C:12]=3[F:29])[CH2:7]2)[CH2:5][CH2:4][CH2:3][CH2:2]1.Br[CH2:31][CH:32]1[CH2:37][CH2:36][O:35][CH2:34][CH2:33]1>>[N:1]1([C@@H:6]2[CH2:10][CH2:9][N:8]([C:11]3[CH:16]=[CH:15][C:14]([N:17]4[CH:26]=[CH:25][C:24]5[C:19](=[CH:20][CH:21]=[C:22]([O:27][CH2:31][CH:32]6[CH2:37][CH2:36][O:35][CH2:34][CH2:33]6)[CH:23]=5)[C:18]4=[O:28])=[CH:13][C:12]=3[F:29])[CH2:7]2)[CH2:2][CH2:3][CH2:4][CH2:5]1

참가 물질

3

반응물 2

HCID 27732864-(Bromomethyl)oxaneHCID 689893502-((R)-4-[1,3']Bipyrrolidinyl-1'-yl-3-fluoro-phenyl)-6-hydroxy-2H-isoquinolin-1-one

생성물 1

HCID 57916900HCID 57916900, 화합물

실험 절차

2-((R)-4-[1,3′]Bipyrrolidinyl-1′-yl-3-fluoro-phenyl)-6-hydroxy-2H-isoquinolin-1-one was reacted with 4-Bromomethyl-tetrahydro-pyran by method K. The product with the molecular weight of 491.61 (C29H34FN3O3) was obtained in this way; MS (ESI): 492 (M+H+).

후처리

  1. customThe product with the molecular weight of 491.61 (C29H34FN3O3) was obtained in this way

출처 및 근거

ORD 기록
ord-4b83a62b467644a9817b9dcc490d030f
출처 데이터셋
uspto-grants-2014_09
특허 번호
US08822495B2

연결된 노트

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