Methyl iodide → 8-(1-Methoxy-cyclopentylmethanesulfonyl)-2-(4-trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decan-1-one

반응식

[CH3:33][I:34].[OH:1][C:2]1([CH2:7][S:8](=[O:9])(=[O:10])[N:11]2[CH2:12][CH2:13][C:14]3([CH2:15][CH2:16][N:17]([c:20]4[cH:21][cH:22][c:23]([O:26][C:27]([F:28])([F:29])[F:30])[cH:24][cH:25]4)[C:18]3=[O:19])[CH2:31][CH2:32]2)[CH2:3][CH2:4][CH2:5][CH2:6]1>>[O:1]([C:2]1([CH2:7][S:8](=[O:9])(=[O:10])[N:11]2[CH2:12][CH2:13][C:14]3([CH2:15][CH2:16][N:17]([c:20]4[cH:21][cH:22][c:23]([O:26][C:27]([F:28])([F:29])[F:30])[cH:24][cH:25]4)[C:18]3=[O:19])[CH2:31][CH2:32]2)[CH2:3][CH2:4][CH2:5][CH2:6]1)[CH3:33]

참가 물질

반응물 2

HCID 6328Methyl iodide

HCID 595780138-(1-Hydroxy-cyclopentylmethanesulfonyl)-2-(4-trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decan-1-one

생성물 1

HCID 595780598-(1-Methoxy-cyclopentylmethanesulfonyl)-2-(4-trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decan-1-one

출처 및 근거

ORD 기록: ord-f74bc2f2bdf84bbe80f66953083004ef
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (3/10)
DOI: 10.1039/C8SC04228D

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