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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 69929생성일: 2026년 10월 25일

3-Amino-6-bromopicolinic acid → trans-(+/-)-Tert-butyl 1-(3-(3-amino-6-bromopicolinamido)pyridin-4-yl)-4-fluoropiperidin-3-ylcarbamate

https://huagongshe.com/reaction/69929

반응식

참여 물질

역할이름HCID투입량
반응물3-Amino-6-bromopicolinic acidHCID 45480452—
반응물HCID 58386807HCID 58386807—
생성물trans-(+/-)-Tert-butyl 1-(3-(3-amino-6-bromopicolinamido)pyridin-4-yl)-4-fluoropiperidin-3-ylcarbamateHCID 88862444—

반응 단계

Following Method 11 of Example 305, trans-(+/−)-tert-butyl 1-(3-aminopyridin-4-yl)-4-fluoropiperidin-3-ylcarbamate and 3-amino-6-bromopicolinic acid were reacted yielding after purification (+/−)-tert-butyl 1-(3-(3-amino-6-bromopicolinamido)pyridin-4-yl)-4-fluoropiperidin-3-ylcarbamate, (20%). LCMS (m/z): 510.9 (MH+).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08822497B2
출처 데이터셋uspto-grants-2014_09
ORD IDord-5b3278def8a849c395f40af2ffc1049a
출처 메모uspto-grants-2014_09