Potassium Cation → 5-{2-[2-amino-6-(4-methylpiperazin-1-yl)pyrimidin-4-yl]-6-fluoro-1,2,3,4-tetrahydroisoquinolin-7-yl}-N-methylpyridine-2-carboxamide

HRID 700696

반응식

[Br:1][c:2]1[c:3]([F:26])[cH:4][c:5]2[c:10]([cH:11]1)[CH2:9][N:8]([c:12]1[n:13][c:14]([NH2:25])[n:15][c:16]([N:18]3[CH2:19][CH2:20][N:21]([CH3:24])[CH2:22][CH2:23]3)[cH:17]1)[CH2:7][CH2:6]2.[C:46](=[O:47])([O-:48])[O-:49].[CH2:55]1[O:56][CH2:57][CH2:58][O:59][CH2:60]1.[CH3:27][NH:28][C:29](=[O:30])[c:31]1[n:32][cH:33][c:34]([B:37]2[O:38][C:39]([CH3:40])([CH3:41])[C:42]([CH3:43])([CH3:44])[O:45]2)[cH:35][cH:36]1.[Cl:52][CH2:53][Cl:54].[K+:50].[K+:51].[OH2:61]>>[c:2]1(-[c:34]2[cH:33][n:32][c:31]([C:29]([NH:28][CH3:27])=[O:30])[cH:36][cH:35]2)[c:3]([F:26])[cH:4][c:5]2[c:10]([cH:11]1)[CH2:9][N:8]([c:12]1[n:13][c:14]([NH2:25])[n:15][c:16]([N:18]3[CH2:19][CH2:20][N:21]([CH3:24])[CH2:22][CH2:23]3)[cH:17]1)[CH2:7][CH2:6]2