Tetrahydrofuran → 3-bromo-4-chloro-1-(1,4-dioxaspiro[4.5]dec-8-yl)-1H-pyrazolo[3,4-d]pyrimidine
반응식
[Br:1][c:2]1[n:3][nH:4][c:5]2[n:6][cH:7][n:8][c:9]([Cl:11])[c:10]12.[CH2:49]1[O:50][CH2:51][CH2:52][CH2:53]1.[CH3:42][CH2:43][CH2:44][CH2:45][CH2:46][CH2:47][CH3:48].[O:12]1[CH2:13][CH2:14][O:15][C:16]12[CH2:17][CH2:18][CH:19]([OH:22])[CH2:20][CH2:21]2.[c:23]1([P:24]([c:25]2[cH:26][cH:27][cH:28][cH:29][cH:30]2)[c:31]2[cH:32][cH:33][cH:34][cH:35][cH:36]2)[cH:37][cH:38][cH:39][cH:40][cH:41]1>>[Br:1][c:2]1[n:3][n:4]([CH:19]2[CH2:18][CH2:17][C:16]3([O:12][CH2:13][CH2:14][O:15]3)[CH2:21][CH2:20]2)[c:5]2[n:6][cH:7][n:8][c:9]([Cl:11])[c:10]12
