Hydrochloric Acid → 4,4-Dimethylcyclohexane-1-carbaldehyde

HRID 70266노트

반응식

HRID 70266 반응식
[CH3:1][C:2]1([CH3:11])[CH2:7][CH2:6][C:5](=[CH:8][O:9]C)[CH2:4][CH2:3]1.Cl>C1COCC1.C(OCC)C.[Cl-].[Na+].O.O>[CH3:1][C:2]1([CH3:11])[CH2:7][CH2:6][CH:5]([CH:8]=[O:9])[CH2:4][CH2:3]1

참가 물질

7

반응물 2

HCID 313Hydrochloric AcidHCID 589086674-Methoxymethylene-1,1-dimethyl-cyclohexane

생성물 1

HCID 222352954,4-Dimethylcyclohexane-1-carbaldehyde

시약·촉매·용매 4

HCID 962Water용매HCID 3283Diethyl Ether용매HCID 8028Tetrahydrofuran용매HCID 57417360Sodium chloride; water용매

실험 절차

A solution of (4,4-dimethyl cyclohexylidene)methyl methyl ether (6.7 g, 0.043 mol) in THF (200 mL) containing 6M HCl (aq) (60 mL) was stirred at room temperature for 24 hr. The reaction mixture was diluted with a mixture of ethyl ether, hexanes, brine and water. The mixture was separated and the aqueous phase was extracted with ethyl ether. The combined organic phase was washed with brine, dried over Na2SO4, and concentrated in vacuo, affording 4,4-dimethylcyclohexanecarbaldehyde as a yellow oil, used without further purification.

후처리

  1. customThe mixture was separated
  2. extractionthe aqueous phase was extracted with ethyl ether
  3. washThe combined organic phase was washed with brine
  4. dry with materialdried over Na2SO4
  5. concentrationconcentrated in vacuo

출처 및 근거

ORD 기록
ord-cdff3e5f4670424e8ceb6362f31354bf
출처 데이터셋
uspto-grants-2014_09
특허 번호
US08822518B2

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