Diisopropylethylamine → HCID 15616401, 화합물

HRID 703413노트

반응식

HRID 703413 반응식
Cl.Cl.[NH2:3][CH:4]1[CH:9]2[CH2:10][CH2:11][N:6]([CH2:7][CH2:8]2)[CH2:5]1.[CH3:12][O:13][C:14]1[CH:25]=[CH:24][C:17]([C:18]([NH:20][C:21](N)=[O:22])=[O:19])=[CH:16][CH:15]=1.C(N(C(C)C)CC)(C)C.C([O-])(=O)/C=C\C([O-])=O>N1C=CC=CC=1>[N:6]12[CH2:11][CH2:10][CH:9]([CH2:8][CH2:7]1)[CH:4]([NH:3][C:21]([NH:20][C:18](=[O:19])[C:17]1[CH:24]=[CH:25][C:14]([O:13][CH3:12])=[CH:15][CH:16]=1)=[O:22])[CH2:5]2

참가 물질

6

반응물 4

HCID 81531DiisopropylethylamineHCID 197853Quinuclidine, 3-amino-, dihydrochlorideHCID 5288227Maleate(2-)HCID 12757374N-Carbamoyl-4-methoxybenzamide

생성물 1

HCID 15616401HCID 15616401, 화합물

시약·촉매·용매 1

HCID 1049Pyridine용매

실험 절차

The above compound was prepared, following the procedure of Example 14b, from 3-aminoquinuclidine dihydrochloride (1.0 g, 5 mmol), 4-methoxybenzoylurea (0.97 g, 5 mmol) and di-isopropylethylamine (1.29 g, 10 mmol) in pyridine (20 ml). The product (1.12 g) was converted to 1:1 maleate half hydrate, mp 166°-168° C.

후처리

  1. customThe above compound was prepared

출처 및 근거

ORD 기록
ord-cd1cc0ddcb664575ad8d34948d9f190b
출처 데이터셋
uspto-grants-1991_01
특허 번호
US04983600

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